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Poruchy metabolismu

Pojmem „poruchy metabolismu“ se rozumí především změna metabolismu bílkovin, cukrů, tuků anebo se jedná o poruchu hospodaření těla s vodou. Nejčastěji je zapříčiněna nedostatkem některého enzymu.

Dna

Artritis urica je odborný název metabolického onemocnění zvaného dna, někdy též nazývaného jako pakostnice či podagra. Vyznačuje se nadměrnou produkcí kyseliny močové. V důsledku jejího nadměrného výskytu v krvi dochází ke koncentraci této látky v kloubech a jiných tkáních, což způsobuje bolest zejména u kloubu palce nohy nebo patního kloubu, zarudnutí a otok postiženého kloubu, někdy může vést k tvorbě ledvinových kamenů, které mohou působit horečku. Touto nemocí trpí asi jeden ze sta mužů ve věku nad 40 let, ale mohou jí trpět i ženy. Může ji způsobit nadměrné požití jídel obsahujících puriny.

Této nemoci můžeme předcházet udržováním ideální hmotnosti (Ta je u každého jedince velice relativní a nedá se přesně určit, ale například Brockův index říká, že dospělý jedinec by měl vážit svou výšku, od které odečte 100. Ženy by se měly od tohoto výsledku 10 % odečíst a muži naopak 10 % přičíst), alkohol požívat v přiměřených dávkách, pít dostatečné množství tekutin a vyvarovat se extrémnímu příjmu bílkovin a aminokyselin.

Je-li stav nemoci akutní, jako první lék použijeme Alupurinol. Vhodná je lázeňská léčba s přesně indikovanými procedurami – fyzioterapie, rehabilitace, akupunktura.

Osteoporóza

Jedná se o onemocnění kostní tkáně, při němž dochází ke křehnutí kostí, což u lidí trpících tímto onemocněním vede k častějším zlomeninám. Většinou bývá způsobena nedostatkem vápníku v těle a zvýšeným odbouráváním kostní tkáně při nedostatku fyzické zátěže, věkem (senilní nad 70 let) nebo podvýživou. Příznaky oteoporózy jsou bolesti zad, zmenšení tělesné váhy a vytvoření hrbu. Proti této nemoci se lze preventivně bránit dostatečeným příjmem vitamínu D, vitamínu K, vápníku a pohybem.

Obezita

Obezitu (česky otylost) způsobuje nadměrné ukládání tuků s překročením normální váhy alespoň o jednu desetinu. Zatímco tuk zdravého člověka tvoří 10 – 15 % tělesné váhy, u obézních lidí se může jednat až o 60 %. Obezita patří mezi nejčastější poruchy metabolismu a bojuje s ní až 40 % obyvatel České republiky a projevuje se u lidí mezi 40. - 60. rokem. U žen (u kterých se často projevuje v pubertě nebo po porodu) se objevuje dvakrát častěji než u mužů. Její příčinou je nepoměr příjmu a výdaje energie, přičemž příjem převyšuje výdej. Příčinou obezity je především nadměrný příjem potravy a s ní spojených kalorií, deprese, nedostatek pohybu a nepravidelné stravování. Doporučuje se pobyt v lázních s cíleným ordinovaným pohybem a zátěžovými procedurami.

Obezitu můžeme rozdělit na dva tipy:

  1. v důsledku onemocnění, dědičné dispozice, poruchy vývoje

  2. v důsledku přebytku energie

Podvýživa

Stav podvýživy nastává v okamžiku, kdy se organismu nedostává dostatečný příjem potravy. Trvá-li hladovění více než 12 hodin, postupně se zmenšuje tělesná hmotnost, neboť je energie čerpána z vlastních zásob. Zprvu se spotřebují glykogen, pak tuky a nakonec bílkoviny. Vhodná je lázeňská léčba se zaměřením na podporu zažívacího traktu.

Cukrovka

Jedná se o metabolické onemocnění způsobené nadměrnou hladinou cukru v krvi. Rozděleujeme jej na dva druhy - DM 1. typu a DM 2. typu. Zatímco DM 1. typu je způsobena nedostatkem inzulinu a vyskytuje se převážně v dětství a mladším věku, tak DM 2. typu je způsobena nedostatečnou citlivostí tkání na inzulin a vyskytuje se u dospělých, především obézních lidí. U DM typu 1 jsou buňky slinivky břišní produkující inzulin ničeny vlastním systémem, jsou tedy řazeny mezi autoimunitní choroby.

Léčba

Jednou z nedílných součástí léčby je dieta a více pohybových aktivit. U DM 1 je nezbytné zahájit léčbu inzulínem, který se aplikuje injekcí pod kůžu a to na břiše, stehně nebo paži a to co možná nejčastěji (3x – 6x denně). Inzulín je hormon bílkovinné povahy, který umožňuje glukóze obsažené v krvi vstup do buněk. U diabetiků, u nichž dochází ke kolísání cukru v krvi, se používá inzulínová pumpa.

U diabetiků postižených nemocí DM 2. typu dochází ve 40 % ke zlepšení cukrovky až normalizaci cukru v krvi po redukci hmotnosti a dietní úpravě. U těch, u kterých dieta nestačí, je nutné podávat léky, které zvyšují výdej inzulínu z beta buněk slinivky břišní nebo které zvyšují citlivost tkání na inzulín. Karlovy Vary jsou indikované jako lázeňské místo s vodoléčbou, rehabilitací, fyzioterapeutickými procedurami a především pitnou kúrou.

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